2.34802 HISTOPATHOLOGY II

This course is conducted by the Discipline of Histopathology.
This course is a continuation of 2.34801, which incorporates Systemic Pathology and Histological Techniques.
Systemic Pathology - This course builds upon the concepts generated in basic pathology on specialization of cells to form tissues, organs and systems. It also explains the signs and symptoms to arrive at an organ system diagnosis. The various laboratory investigations are taught to allow the student to understand the roles they will play in assisting the physician to arrive at a diagnosis and assist in patient management. The topics to be covered will consist of the cardiovascular, respiratory, gastrointestinal, reticuloendothelial (MPS), musculoskeletal, skin, endocrine and nervous system.

Histological Techniques - Special staining techniques for lipids, proteins and nucleic acids, abnormal protein deposition and nervous system. Introduction to enzyme histochemistry and immunohistochemistry as diagnostic tools. Introduction to cytological investigations; sampling and smear preparation techniques from FNA, sputum, effusion. Introduction to cervical cytology.

Aims: To develop a basic understanding of the ways in which disease processes affect the structure and functions of cells and tissues enabling the diagnosis of specific diseases by histopathology;
To develop competence in the important laboratory techniques used in histopathology and gain an understanding of the principles and practical objectives of these techniques as they are used in the diagnostic process.

Contact hours: 6 hours per week (2 lectures, 1 tutorial, 3 practical).

Assessment: Course work (assignments, tests, practical write-up) 60%, final exam (theory & practical) 40%.

Reference Textbook

Bancroft, J. D., & Stevens, A., Theory and practice of histological techniques, 3rd Ed. Churchill Livingstone, Edinburgh, 1990

Coltran, R.S., Kumar, V., Collins T., Robbin's pathologic basis of diseases, 6th Ed., Harcourt Asia, 1999